What's your experience?

Most of the time? It's been fine when I use Proton + Steam (on Experimental). Not everyone likes Steam though and it is a bit of a pain to use Proton outside of it. Wine itself is alright but I really hate wineprefixes. Why can't it be some sort of kernel-layer where it translates Windows shit into Linux natively as if every dll was made into a so? Why do I gotta have a fake windows drive with fake mounting?

I don't usually run normal applications on Wine. The majority of my use comes with games, old and new.

For games it's alright, I'd say. A lot of programs aren't worth the headache in my opinion so I just run them on a windows VM.

it struggles with 4k sometimes, but other than that it's fine

>>4382
A VM is easier? You wait for however long the Windows bloat loads up for and to do what? Open a special file? I may have shat on wineprefixes but I'd find setting those up quicker in the long run than a VM IMHO. It's also less resource intensive.

>>4391
Mainly for things I can't for the life of me get to work correctly in wine. A recent example was trying to do the bitrec patches for FO4. I might just be dumb but I couldn't get it to work with powershell, so I just did the patches in the VM and transferred it back.

>>4392
I guess that does make sense. I've got my own VM just in case but I've found myself using it less and less, especially within the last decade.

some shit software i had to use (NI Multisim) doesnt work on wine no matter what kind of thingamajigs you plan on doing
recently 64 bit wine started to emulate WoW64 thingy so now all touhou games (32 bit) are slow as fuck thanks to it and i have to use proton instead
paint.net doesnt work either

other than that it works pretty well i guess

I use Lutris for playing games lately, and am impressed with how it handles games. A funny one was Deus Ex, every time I played on Windows I'd get stuck at the second mission because the water lag would irritate me, but running on Wine it had flawless performance. Started playing Kingdom Come Deliverance, and was impressed that my cheapo desktop, older graphics card, running the game through Wine, is totally wiping the floor against a PS4 Pro, which couldn't run KCD at a stable framerate.
Most of my games aren't very demanding though, and often have native Linux builds. Zachtronics and Subset games, Rimworld, etc.
I recall one problem though. Couldn't play videos from the first Thief game, just skips them. I didn't mind at first, but felt like I was missing something when I ran into the zombies into the mine.

For Proton, I find that it's hit or miss depending on the program I'm running. Game doesn't work in this version , so it works in another version. Doesn't take that long to mess around with and isn't a brainfuck of a issue. Wine on the other hand was more hands on with getting certain things to work but nowadays I don't touch wine simply because I avoid things that require it , all my games work through proton. ( Non Steam game I simply add to my library and run through proton )